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KMID : 0352119920080010068
Journal of Kyung Hee University
1992 Volume.8 No. 1 p.68 ~ p.84
Effects of Euphorbia kansui T. N. ex T.P. Wang on Rats with Acute Renal Failure Induced by Gentamicin Sulfate



Abstract
This article is to investiagte the effects of Euphorbia kansui T. N. Liou ex T. P. Wang on rats with acute renal failure induced by gentamicin sulfate.
So this experimental research was focused on measuring ¨ç the levels of creatinine, blood urea nitrogen, glutamic oxaloacetic transaminase, glutamic pyruvic transaminase, total protein, sodium, potassium and chloride in the serum and ¨è the
levels
of
protein, blood, sodium potassium, chloride, pH, specific gravity and volume in the urine and ¨é intake water.
@ES The results were summarized as follows.
@EN 1) While the levels of creatinine, blood urea nitrogen, potassium, glutamic oxaloacrtic transaminase and glutamic pyruvic transaminase in the serum were significantly increased, the level of chloride in the serum was significantly decreased
and
that
of sodium in the serum was partially decreased on the Euphorbia kansui T. N. Liou ex T. P. Wang group.
2) While the levels of sodium and chloride in the urine were significantly increased, proteinuria and urine volume were partially increased, the level of potassium in the urine was significantly decreased and the specific gravity of urine was
partilly
decreased.
According to the above results, it is shown that Euphorbia kansui T. N. Liou ex T. P. Wang without refinning had an partial diuretic effect on rats with acute renal failure induced by gentamicin sulfate, but aggravated the glomerular fitration
rate
and
tubular reabsorption. So, it is supposed that Euphorbia kansui T. N. Liou ex T. P. Wang without refinning needs to be used carefully on acute renal failure induced by gentamicin sulfate and it is necessary to futhermore research about the kinds
of
extracts from: refined, weter-alcohol mixed boiling and powder.
KEYWORD
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